Lambert-Eaton myasthenic syndrome (LEMS) is a very rare disease, with researchers estimating it affects about one person in every one million. Like many rare diseases, LEMS could well be underdiagnosed, especially in an aging population. Few physicians are very familiar with the disease, and many may never…
Health Insights
Firdapse and Ruzurgi to Treat LEMS
Lambert-Eaton myasthenic syndrome (LEMS) is a rare autoimmune disease that affects the neuromuscular junction — the point at which nerve and muscle cells meet. The disease leads to muscle weakness, pain, and fatigue, among other symptoms. With no current cure, LEMS can be treated…
How to Make the Most of Our LEMS Forums
Our forums for Lambert-Eaton myasthenic syndrome (LEMS) are now live. If you have LEMS or a loved one with the condition, you may be wondering who these forums are for and how to use them. Here are answers to these questions and some others: Who are the forums for? The…
Distinguishing Carpal Tunnel Syndrome and LEMS
Many of the symptoms of Lambert-Eaton myasthenic syndrome (LEMS) — notably muscle weakness, pain, and fatigue, as well as tingling in the hands and feet — can be very similar to another condition called carpal tunnel syndrome. It can, therefore, be difficult to distinguish the two conditions.
LEMS and Clinical Trials
While no cure currently exists for Lambert-Eaton myasthenic syndrome (LEMS), researchers are working on developing new treatments. Clinical trials are essential steps in this process. Here is information that may help you to decide whether you would like to join a LEMS clinical trial. What is a clinical trial?…
Should My Baby Be Tested for LEMS?
If you or your partner has Lambert-Eaton myasthenic syndrome (LEMS), you may be wondering whether your baby should be tested for this disease. About LEMS LEMS is a rare autoimmune disease in which the body produces autoantibodies that attack the neuromuscular junction — the point at which nerve and…
Vaccines and LEMS
Many patients with an autoimmune disease such as Lambert-Eaton myasthenic syndrome (LEMS) may wonder whether it is safe for them to get vaccines. What are vaccines? Vaccines are treatments that stimulate your immune system to produce antibodies against disease. They usually contain either dead or weakened virus…
LEMS and Anesthesia
Lambert-Eaton myasthenic syndrome (LEMS) is a rare autoimmune disease that affects the connection between nerve and muscle cells. Patients’ bodies produce antibodies that mistakenly attack this connection, and the muscles grow weak as a result. The abnormalities in nerve signaling mean that patients may have an atypical response…
Tips for Dealing With Pain When You Have LEMS
Lambert-Eaton myasthenic syndrome (LEMS) is a rare autoimmune disorder that affects the nerve cells controlling muscle movement. In addition to muscle weakness, fatigue, and eye problems, pain is a common symptom of LEMS. Here are some ways to help you cope. What causes pain in…
Medications to Avoid When You Have LEMS
Lambert-Eaton myasthenic syndrome (LEMS) is a rare autoimmune disease that primarily affects nerve cells and muscles. The immune system mistakenly attacks a specific component of the nervous system that controls muscle contractions. This results in muscle weakness, among other symptoms. There are some medications that you should…
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- After 6 years, my daughter changed her LEMS treatment plan March 16, 2026