News

Repeated testing of electrical signaling in muscles before and after exercise is a key test for diagnosing Lambert-Eaton myasthenic syndrome (LEMS), a new case report highlights. The case was discussed at the 32nd International Congress of Clinical Neurophysiology (ICCN) of the IFCN, Sept. 4–8 in Geneva, Switzerland, in a…

The prevalence of Lambert-Eaton myasthenic syndrome (LEMS) in Japan is similar to that of other countries, affecting approximately 2.7 out of every one million people in the country. That is according to a study, “Nationwide survey of Lambert-Eaton myasthenic syndrome in Japan,” published in the journal…

Muscle responses to low-frequency repetitive nerve stimulation in people with Lambert-Eaton myasthenic syndrome (LEMS) were different from those of patients with myasthenia gravis (MG), a study reported. Because LEMS and MG are both autoimmune diseases marked by muscle weakness and other overlapping symptoms, this test may help distinguish…

An elderly woman treated with three courses of pembrolizumab — known by its brand name Keytruda — for a type of lung cancer, called non-small cell lung cancer, had her symptoms of Lambert-Eaton myasthenic syndrome (LEMS) return after more than 20 years, according to a report from Japan.

The diagnostic journey of a man in his early 30s with progressive muscle weakness that was ultimately determined to be due to Lambert-Eaton myasthenic syndrome (LEMS) was described in a recent case report. The report, “Progressive motor quadriparesis with wasting: a diagnostic conundrum,” was published in BMJ Case…

Plasma exchange therapy eased the symptoms of a man with Lambert-Eaton myasthenic syndrome (LEMS) who tested negative for disease-related autoantibodies, according to a case series study. Researchers noted that a diagnosis of LEMS often relies on the presence of autoantibodies — immune proteins that mistakenly target a…

The Inflation Reduction Act, a large bill designed to tackle healthcare costs as well as climate change and inflation, was passed by the U.S. Congress and awaits the president’s signature this afternoon, making it law. In a recent statement, the National Organization for Rare Disorders (NORD) highlighted that some…

Patients diagnosed with Lambert-Eaton myasthenic syndrome (LEMS) with no identifiable cause should be continuously followed for signs of cancer, according to a recent case report. The researchers’ suggestion was supported by the case of a 64-year-old man who was diagnosed with LEMS at their clinic, and in whom lung…

Misdiagnosis and delayed diagnosis are common among people with lung cancer-associated Lambert-Eaton myasthenic syndrome (LEMS), according to a small study in China. Most patients showed signs of LEMS before their lung cancer diagnosis — such as muscle weakness and problems in the autonomic nervous system, which controls involuntary functions such as…

A total of 30 patient advocacy groups working to further understanding and the needs of people living with rare diseases have been selected to receive a Horizon Therapeutics‘ #RAREis Global Advocate Grant. Winners of this year’s inaugural awards are spread across nine countries and represent a total of 29 rare…