News

Stimulated Single-Fiber Electromyography an Accurate Diagnostic Tool in LEMS, Case Report Suggests

Using stimulated single-fiber electromyography is associated with an early and accurate diagnosis of Lambert-Eaton myasthenic syndrome, according to a case report. The study, “Stimulated single-fiber electromyography (sSFEMG) in Lambert-Eaton syndrome,” was published in the journal Clinical Neurophysiology Practice. Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune disease that…

Diagnostic Test May Not be Highly Specific for LEMS, Study Warns

Contrary to current thinking, testing for levels of antibodies against voltage-gated calcium channels may not be highly specific for Lambert-Eaton myasthenic syndrome (LEMS), researchers caution in a recent study. The study, “Low specificity of voltage-gated calcium channel antibodies in Lambert-Eaton myasthenic syndrome: a call for caution,” was published…

FDA Accepts Catalyst’s NDA for Firdapse with Priority Review Status for LEMS

The U.S. Food and Drug Administration has accepted Catalyst Pharmaceuticals’ new drug application (NDA) for Firdapse (amifampridine phosphate) for Lambert-Eaton myasthenic syndrome (LEMS), with priority review status. Firdapse is a formulation of amifampridine phosphate in development for the treatment of LEMS as well as other conditions. Several clinical studies have…