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Subcutaneous IVIG (SubQ Ig) for LEMS – has anyone tried it?
Most people with LEMS who receive immunoglobulin therapy are familiar with IVIG infusions given through a vein (intravenously). But there’s another option some patients are now using: Subcutaneous IVIG (or SubQ Ig)—injected under the skin instead of into a vein.
SubQ Ig allows you to give yourself smaller doses more frequently (usually at home), which may offer greater independence and fewer side effects. It’s commonly used in other autoimmune and neuromuscular disorders—but what about in LEMS?
If you’ve made the switch, how was the transition to subq IG? Did you notice a difference in your LEMS symptoms or recovery from IG? How often do you administer your doses, and how long does it take?
It’s more convenient for those who have trouble with IV access or frequent travel to infusion centers.
There’s limited data on SubQ Ig use specifically in LEMS—so patient stories really matter here.
A few reminders:
SubQ Ig may not be the right fit for everyone—especially those who need rapid symptom control.It’s important to track your symptom response carefully with your neurologist when transitioning.
Training and support are essential when learning to self-administer at home.
Are you currently using SubQ Ig, or thinking about switching from IVIG?
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