Lambert-Eaton News Forums Forums Living With LEMS What medications trigger your LEMS?

  • What medications trigger your LEMS?

    Posted by Ashley on April 16, 2025 at 8:06 am

    Good morning!

    If you’ve been diagnosed with Lambert-Eaton Syndrome, you know how important it is to manage your symptoms and improve your quality of life.

    However, some medications can make your muscle weakness worse or interfere with your treatment. It’s essential to understand which drugs might be harmful and to talk to your doctor about alternatives.

    Common Medications That May Make LEMS Symptoms Worse:

    Statins: Often used to lower cholesterol, statins can sometimes cause muscle problems, which may worsen your weakness.

    Calcium Channel Blockers: These medications for heart issues can interfere with the way your nerves communicate with muscles, potentially making weakness worse.

    Certain Antibiotics: Some antibiotics, especially those in the fluoroquinolone family, can affect how your muscles function and increase weakness.

    Anesthesia: Drugs used during surgery or procedures may impact your muscles, so it’s essential to let your healthcare team know about your LEMS diagnosis.

    Have you noticed any specific medications that seem to flare your LEMS symptoms?

    Ashley replied 2 months, 2 weeks ago 2 Members · 2 Replies
  • 2 Replies
  • Wanda Grischkowsky

    Member
    April 29, 2025 at 5:23 pm

    I am taking a statin three days per week. I tried Repatha injections but it increased my glucose. So, back on atorvastatin. Although I am taking a small dose, I’m wondering if it is the cause of my high CK levels. I have moderate to severe muscle pain each day.

    • Ashley

      Member
      May 5, 2025 at 8:03 am

      Hey @Wanda Grischkowsky I don’t know much about lab values associated with statins but it could be plausible! I would definitely bring it up to whomever prescribes it for you.

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