6 Signs of Chronic Fatigue in LEMS

Emily Malcolm, PhD avatar

by Emily Malcolm, PhD |

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Lambert-Eaton myasthenic syndrome (LEMS) is a rare autoimmune disease that affects the muscles, causing weakness. Many patients also experience chronic fatigue as a result of this disease. Symptoms often develop gradually, which makes it easy to overlook subtle ones such as fatigue.

Here are six signs of chronic fatigue to watch for:

Tiredness or exhaustion

Do you feel tired all the time, even after a good night’s sleep? Do daily tasks make you feel more tired than they should?

Trouble sleeping

Do you have trouble falling asleep? Do you find that a full night’s sleep does not leave you feeling refreshed? These can be signs of chronic fatigue.

Loss of memory or concentration

Fatigue makes it hard to remember and to concentrate. Do you find your attention wandering, even when you are thinking about the things you enjoy? Do you have trouble remembering things you’ve been told?


Fatigue can make it easier to catch colds and flu. Do you frequently get sore throats? Do you have unexplained joint pain that saps your energy?


Do you experience dizziness or nausea? These problems may be caused by fatigue.


Are you easily irritated? Do you have rapid mood swings? For example, do you get angry, and then suddenly find yourself crying or laughing?

If you think you may have chronic fatigue, it is a good idea to discuss it with your physician.


Last updated: Aug. 13, 2019


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