Medications to avoid in LEMS (and Myasthenia)

[DCarpenter]

Hi all, listed below is an NIH url with drugs to avoid

Table – PMC (nih.gov)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7457047/table/T1/?report=objectonly

hope helpful.  Deborah Carpenter

[Ashley]

Thank you @Deborah Carpenter for sharing this!

[LUCIA]

Muchas gracias por la lista de medicamentos que interfieren o son negativos para crisis o brotes del eaton lambert. La verdad es que me encuentro muchas veces sometida a este tipo de medicamentos por los efectos secundarios que provoca el mismo sindrome autoinmune fisica y psíquicamente y que son bastante interferientes, pero no me los pueden eliminar con lo que el estado general anda sosteniendote así así de milagro, pero quizás si ocasionen alguna crisis mas o menos importante de la enfermedad.
Creo que un ajuste de todo y en pocas dosis pueda lograr ese equilibrio que tanto necesitamos.

Thank you very much for the list of medications that interfere or are negative for eaton lambert crises or outbreaks. The truth is that I often find myself subjected to this type of medication due to the side effects caused by the same autoimmune syndrome physically and mentally and which are quite interfering, but they cannot eliminate them with what the general state is holding you like this. miracle, but perhaps if they cause a more or less important crisis of the disease.
I believe that an adjustment of everything and in a few doses can achieve that balance that we need so much.

[Ashley]

Hola Lucia¡

Gracias por tu opinión! Como dijiste, cada persona es diferente y a veces los beneficios de un medicamento pueden superar el riesgo. Por ejemplo, los betabloqueantes están “contraindicados” para el LEMS, pero tengo que tomar propranolol para mantener mi POTS bajo control. No he notado que empeore mi LEMS y he estado tomándolo durante muchos, muchos años.

Siempre debemos hablar con nuestros médicos si nos preocupa que un medicamento pueda empeorar nuestro LEMS y considerar que a veces el beneficio puede superar el riesgo y estar abiertos a experimentar (bajo supervisión) cuando sea médicamente necesario.

Hey

@LUCIA

Thank you for your input! Like you said, everyone is different and sometimes the benefits of a medication may outweigh the risk. For example, beta blockers are “contraindicated” for LEMS, but I have to take propranolol to keep my POTS under control. I haven’t found that it makes my LEMS worse and have been on it for many, many years.

We should always talk with our doctors if we are concerned that a medication may worsen our LEMS and consider that sometimes the benefit may outweigh the risk and be open to experimenting (under supervision) when it is medically necessary.

[Peggy]

Thank you for this list

I’m on Imuran and doing pretty well but my liver functions are elevated and going up

My general dr wants me to start on a cholesterol hovering med saying it will help liver most of these have side effects of muscle pain and weakness

Has anyone had this situation or have input on what they were able to do to help high liver functions due to meds

Thanks so much

Peg

[Ashley]

Hey @Peggy Sorry to hear about your liver function, I know that is so frustrating! I can make a topic about this next week to see if anyone else here has experience with this!

[Peggy]

That would be great

I’m is a pinch because imuran helps so much

I’d like to hear about others

Thank you!

[Ashley]

No problem! I’m happy to help! 🙂